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    "abstract" : [ "Speicheldrüsenkarzinome stellen eine histologisch äußerst heterogene Gruppe von Tumoren der großen und kleinen Speicheldrüsen im oberen Aerodigestivtrakt dar. Die Behandlung der Karzinome der großen Speicheldrüsen folgt überwiegend gemeinsamen Prinzipien, während sich die Behandlung der Tumoren der kleinen Speicheldrüsen eher an der Lokalisation und den Behandlungsprinzipien für Kopf-Hals-Karzinome derselben Lokalisation richtet. In dieser Leitlinie werden nur die Karzinome der Speicheldrüsen dargestellt. Die enge interdisziplinäre Zusammenarbeit der einzelnen beteiligten Fachdisziplinen ist für die optimale Behandlung von Patientinnen und Patienten (Pat.) mit Speicheldrüsenkarzinomen eine wichtige Voraussetzung. Bei Speicheldrüsenkarzinomen wird sowohl in den frühen als auch bei den lokal fortgeschrittenen Tumoren ein kurativer Therapieansatz verfolgt. Kurative Therapie der Wahl ist die Operation des Primärtumors und gegebenenfalls der lokoregionären Halsmetastasen. Die definitive Radio(chemo)therapie erfolgt bei Pat., die nicht operiert werden können. Bei Risikopatienten erfolgt im Anschluss eine postoperative Radiotherapie. Die medikamentöse Tumortherapie ist den nicht kurativ behandelbaren Tumoren mit Fernmetastasen oder Rezidivtumoren vorbehalten, die nicht durch eine Lokaltherapie behandelt werden können. In den letzten Jahren hat insbesondere für die Rezidivtumoren die molekulare Diagnostik an Bedeutung gewonnen, um eine personalisierte Therapieentscheidung für Rezidivtumoren oder Tumoren mit Fernmetastasen treffen zu können." ],
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